A puppy with a growth that resembles a tail on his head is gaining national attention, and the animal rescue caring for him hopes the publicity will help other dogs in the community.

Due to NBC News' coverage of the House impeachment inquiry hearings, Days of Our Lives may be aired on a different channel on Friday, November 15.

Federal transportation safety investigators criticized the U.S. Coast Guard Wednesday for ignoring suggestions over nearly two decades to improve tourist duck boats, changes they say might have prevented last year's Missouri accident that killed 17 people.

A current list of closures in the Local 6 region. 

Use caution on bridges and overpasses, don't use cruise control, approach intersections with care and signal lanes changes.

Innovative emergency departments around the country are taking the lead and offering specialized care to these elderly patients.

CARBONDALE, IL— Carbondale police have released the identities of two suspects wanted in connection to murder.

Results are in for the 4 ballot questions in southeast Missouri.

Daylight saving time ends at Sunday at 2 a.m. 

Around 12:45 a.m., Cape Girardeau police were called to the 2800 block of Whitener Street on report of gun shots fired.

Halloween is here and that means it is time to put on your costumes!

The hearing at a downtown St. Louis state office building is expected to last five days and a ruling isn't expected until February at the earliest.

The Cape Girardeau, Missouri, Police Department says human remains were found in the city Friday.

This year's event will be held on Saturday, October 26 from 10 a.m. - 2 p.m.

CAPE GIRARDEAU, MO — A Cape Girardeau, Missouri, woman has claimed the $3 million Mega Millions prize she won with a ticket bought at a Schnucks Market earlier this month.

A 5-year-old girl died Monday at a hospital, a day after the blaze broke out at the Clinton-Peabody public housing complex. A 6-month-old boy was found dead by firefighters who responded to the blaze. A third child, a 4-year-old girl, is in critical condition.

A Missouri group pushing to expand access to voting is going to court over how the state's top election official wants to describe the proposal to voters.

A missing Missouri man was found at the bottom of a ravine by a biker, one week after crashing his car.

The Local 6 area sits on the New Madrid Seismic Zone and someday a major earthquake could hit the area. Are you prepared?

A Kansas City, MO man is recovering after striking a concrete barrier on his motorcycle and being thrown 47 feet off the side of the highway. 

Missouri Department of Conservation officials say the state's elk herd is on track to be large enough in 2020 for the first hunt in more than a century.

The Missouri Lottery says a $3 million Mega Millions ticket was sold in Cape Girardeau, matching all five numbers of Tuesday night's drawing. 

Jurors have ruled that an 86-year-old former Missouri minister is a sexually violent predator who should remain confined.

A state appeals court has sided with Missouri prison guards who alleged they were shorted on their pay in a lawsuit that could cost taxpayers $125 million.

One suspect in the Kansas bar shooting that left four men dead and five people injured has been arrested and a second suspect has been identified.

Longtime Missouri news anchor Mike Shain has died. He was 80 years old. 

An $8,000 reward is being offered for information in the case of a pet beagle that was skinned alive in southwest Missouri.

A Missouri man was executed Tuesday for killing a man during a violent 1996 crime spree in southeast Missouri, despite concerns that the inmate's rare medical condition would cause a gruesome lethal injection.

Russell Bucklew, 51, is scheduled to die by lethal injection at 6 p.m. (7 p.m. ET) Tuesday. He was convicted of first degree murder, kidnapping, and first degree burglary in 1997.

The cave figured prominently in Twain's book, "The Adventures of Tom Sawyer," published in 1876, and became famous thereafter.

National Voter Registration Day is held on the fourth Tuesday in September.

Authorities say a man and a boy whose bodies were found last week died in a murder-suicide.

A Jefferson City man is accused of threatening to shooting people at a Walmart where he worked.

You'll soon be able to buy beer and wine at more Southeast Missouri State University home games.

Southeast Missouri State University will discuss the school's alcohol and medical marijuana policies on Friday.

The Missouri man is the state's first death related to an outbreak of lung disease linked to e-cigarettes or other vaping-related devices, the Missouri Department of Health and Senior Services said. 

A federal judge has denied a request by Missouri to allow a ban on abortions after 20 weeks of pregnancy to go into effect while the state waits for further court action.

Here's a list of upcoming road closures and traffic alerts for the week of Sept. 16-22.

Chief J. McMillen says the comments were made two days ago on a public Facebook account.

Missouri Attorney General Eric Schmitt on Friday will release details of a lengthy investigation into sex crimes involving Roman Catholic clergy.

Parson met with St. Louis Mayor Lyda Krewson, St. Louis County Executive Sam Page and about a dozen other area leaders to address violence in the city. 

Missouri Republican Gov. Mike Parson says he's running to keep his seat.

The man was arrested and charged with making terroristic threats

The Missouri Supreme Court has ruled that a lawsuit filed over the Rams' departure from St. Louis in 2016 will be heard in a St. Louis courtroom.

UPDATE: A woman accused of shooting her mother in southeast Missouri is in custody. 

When the congregation moved out of a century-old Methodist church in St. Louis, the building could have turned into a vacant eyesore. Instead, Lisa and Dan Macheca bought it and turned it into a bed and breakfast.

The Missouri Department of Corrections is partnering with a university to launch college-level classes designed to train murderers, rapists and other long-term inmates to be ministers.