Two men are in custody after officers were shot at and a police vehicle was intentionally rammed during a chase that began in Cape Girardeau and ended in Illinois.

Police in Kansas City, Missouri, say at least two people are dead and 15 people were reportedly injured in a shooting outside a bar.

Damage was left behind, but no injuries were reported.

The country duo has announced a US tour, with 18 dates beginning in May in St. Louis, Missouri.

The governor is expected to talk about the state budget and his plans for the state's future.

Authorities said she gave birth to the twins — a boy and a girl — and then covered their mouths and noses with a towel.

We have activated a Weather Authority Alert for tonight into Saturday. A line of storms is expected to pass across the area with flash flooding, high winds, and a tornado all possible.

Police are looking for a man suspected of stealing a charity donation jar from a business in Poplar Bluff, Missouri.

A man stole a pickup truck with a sleeping passenger and a goat inside it and drove it all the way from Missouri to Oklahoma before releasing the terrified victim and animal and eventually being arrested.

With 2019 almost behind us, we're taking a look back at the biggest local stories of the year.

Many people in the Local 6 area need a place to go for a hot meal on Christmas.

The city council in Wausau, Wisconsin, is looking to tweak a nearly 50-year-old law prohibiting throwing snowballs within city limits.

A Missouri lawmaker wants to put the brakes on transportation officials’ use of playful messages on electronic signs mounted along state highways, such as “Santa’s Coming Have you Been A Good Driver” and “Treat the Road Like a Cat Video ... Share It.”

The fire was in the men's restroom in the front lobby.

15-year-old Mariyiah C. Turner was reported as a runaway by her family on November 19.

The threats were made on Snapchat.

16-year-old Aniyah A.M. Jones was reported as a runaway by her family. She was last seen on November 19.

Police have issued warrants for two 19-year-old men in connection to a deadly shooting in Cape Girardeau, Missouri. They are both considered armed and dangerous, investigators say.

Lawyers for a Missouri doctor who impregnated a 16-year-old Kentucky girl say the doctor's marriage to the girl is valid and a legitimate defense to child pornography charges.

Friday, Dec. 13 is the last day to donate to the Spirit of Giving Toy Drive. 

Investigators in Cape Girardeau, Missouri, have released the name of a man who died after he was shot multiple times Wednesday. 

Law enforcement agencies are investigating a deadly shooting that happened Wednesday in Cape Girardeau, Missouri. 

As we enter the final push to help ensure local children get gifts this Christmas, it's not too late to give or to receive.

A Morley, Missouri man was arrested Saturday on multiple warrants. The Scott County Sheriff's Office says deputies arrested 24-year-old Christian Montgomery, who had been considered armed and dangerous.

After the July 2018 sinking at Table Rock Lake near Branson, multiple lawsuits were filed against Ride the Ducks International, which owned the boat before Ripley Entertainment bought it.

A dog that drew international attention because of a tail-like growth on his face will remain with the founder of a group that rescued him.

The Kentucky Transportation Cabinet says the Dorena-Hickman Ferry is closed Sunday, Dec. 1, due to high winds.

Two children and an adult were killed after two cars were swept off the road in Bollinger County, Mo. 

(CNN) -- While much of America was gathering around a dining table on Thanksgiving, this hospital stayed busy caring for not one, not two, not even three, but 12 sets of newborn twins.

Across the country, communities are preparing to serve free Thanksgiving meals to their neighbors. Here's a list of places where you can get a free Thanksgiving meal in the Local 6 area. 

Ensuring minors, domestic abusers and violent offenders don’t have access to guns is “commonsense” and “doable” for the Republican-led Legislature, where there’s strong support for gun rights, Gov. Mike Parson said. 

The family of a Murray State student who died in a boating accident said they raised money for Calloway County Fire-Rescue to not only help other families, but to honor their daughter's helping spirit.

The products were sold in 22 states including Illinois and Missouri.

A Missouri woman has been charged with first-degree murder and armed criminal action in the death of her 51-year-old daughter.

Human remains were found in October in Cape Girardeau, Missouri. Now, police say investigators have identified them.

Cape Girardeau police had been looking for 36-year-old Jeremiah Ramone Twiggs since August.

A pedestrian was hit by a train in Cape Girardeau, Missouri, Saturday night.

A huge show of support came out for a 14-year-old Missouri boy who died after a four-year battle with cancer.

ST. LOUIS (AP) — A Missouri woman is accused of stealing $400,000 from the small town where she formerly worked, and $156,000 from a charity.

A puppy with a growth that resembles a tail on his head is gaining national attention, and the animal rescue caring for him hopes the publicity will help other dogs in the community.

Due to NBC News' coverage of the House impeachment inquiry hearings, Days of Our Lives may be aired on a different channel on Friday, November 15.

Federal transportation safety investigators criticized the U.S. Coast Guard Wednesday for ignoring suggestions over nearly two decades to improve tourist duck boats, changes they say might have prevented last year's Missouri accident that killed 17 people.

A current list of closures in the Local 6 region. 

Use caution on bridges and overpasses, don't use cruise control, approach intersections with care and signal lanes changes.

Innovative emergency departments around the country are taking the lead and offering specialized care to these elderly patients.

CARBONDALE, IL— Carbondale police have released the identities of two suspects wanted in connection to murder.

Results are in for the 4 ballot questions in southeast Missouri.

Daylight saving time ends at Sunday at 2 a.m.